M.D. Ezgi Topyıldız is a pediatric immunology and allergy specialist trained at Ege University Faculty of Medicine, where she completed her training in Pediatric Immunology and Allergy Diseases in 2022. She currently practices with Acibadem Health Group (since 2024), providing care for children and adolescents with allergic and immunologic conditions. Her clinical interests include primary immunodeficiencies, allergic diseases in childhood, diagnostic immunology, and individualized management plans that blend evidence-based care with family-centered communication. M.D. Topyıldız is committed to staying current with advances in immunology and allergy through active involvement in professional societies. Professional memberships – European Society for Immunodeficiencies (ESID) – European Academy of Allergy and Clinical Immunology (EAACI) – Turkish National Society of Allergy and Clinical Immunology – Society of Clinical Immunology M.D. Topyıldız is known for her thoughtful approach to complex cases and for working closely with families to improve quality of life for her young patients.
Education
- 2022 Ege University Faculty of Medicine Pediatric Immunology and Allergy Diseases
- 2016 Istanbul University Istanbul Faculty of Medicine Pediatrics
- 2011 Istanbul University Cerrahpasa Faculty of Medicine
Experience
- 2024 Acibadem Health Group
- 2023 – 2024 Hatay Training and Research Hospital
- 2019 – 2023 Ege University Faculty of Medicine Hospital
- 2016 – 2019 Ministry of Health University Zeynep Kamil Training and Research Hospital
- 2012 – 2016 Istanbul University Istanbul Faculty of Medicine
Memberships
- European Society Immunodeficiencies (ESID)
- Turkish National Society of Allergy and Clinical Immunology
- European Academy of Allergy and Clinical Immunology (EAACI)
- Turkish National Society of Allergy and Clinical Immunology
- Society of Clinical Immunology
Publications
- Current genetic defects in common variable immunodeficiency patients on the geography between Europe and Asia: a single-center experience.
Immunologic Research 72, no. 2 (2024): 225-233. Aygun, Ayse, Ezgi Topyıldız, Mehmet Geyik, Neslihan Edeer Karaca, Asude Durmaz, Guzide Aksu, Ayca Aykut, and Necil Kutukculer - Facilitated Subcutaneous Immunoglobulin Treatment Increases the Quality of Life and Decreases the Number of Infections and Hospitalizations in Children with Primary Immunodeficiencies
International Archives of Allergy and Immunology 185, no. 4 (2024): 382-391. Erbaş Açıcı, Nida, Ezgi Topyildiz, Ayşe Aygün, Mehmet Geyik, Neslihan Edeer Karaca, Guzide Aksu, and Necil Kutukculer. - MHC Class II Deficiency: Clinical, Immunological, and Genetic Insights in a Large Multicenter Cohort.
The Journal of Allergy and Clinical Immunology: In Practice 12, no. 9 (2024): 2490-2502 Koksal, Zeynep Gulec, Sevgi Bilgic Eltan, Ezgi Topyildiz, Ahmet Sezer, Sevgi Keles, Figen Celebi Celik, Aylin Ozhan Kont et al. - Autoimmune Cytopenias Are Highly Associated with Inborn Errors of Immunity and They May Be the Initial Presentations in Cases without Severe Infections.
International Archives of Allergy and Immunology 185, no. 4 (2024): 392-401. Taskin, Raziye Burcu, Ezgi Topyıldız, Neslihan Edeer Karaca, Guzide Aksu, Deniz Yılmaz Karapınar, and Necil Kutukculer. - Factors effecting natural course of egg allergy.
Eur Ann Allergy Clin Immunol 56, no. 3 (2024): 116-120. Şenol, Handan Duman, Mehmet Geyik, Ezgi Topyıldız, Ayşe Aygün, Figen Gülen, and Esen Demir. - Transient hypogammaglobulinemia of infancy and unclassified syndromic immunodeficiencies are highly common in oesophageal atresia patients.
Scandinavian Journal of Immunology 99, no. 2 (2024): e13338. Ulman, Hilmican, Ayşe Aygün, Deniz Çağlar, Zafer Dökümcü, Ezgi Topyıldız, Ata Erdener, Güzide Aksu, Neslihan Edeer Karaca, Coşkun Özcan, and Necil Küt - Alterations in B and NK cells highly correlate with disease severity in children with COVID-19.
Turkish Journal of Medical Sciences 53, no. 5 (2023): 1205-1213 Topyildiz, Ezgi, Neslihan Karaca, Raziye Burcu Taşkın, Ayşe Aygün, Zümrüt Şahbudak Bal, Eylem Ulaş Saz, Nuri Zafer Kurugöl, Necil Kütükçüler, and Güzi - Successful treatment of post-pericardiotomy syndrome via C1 inhibitor replacement therapy in a hereditary angioedema patient with Marfan syndrome.
The Turkish Journal of Pediatrics 65, no. 2 (2023): 338-343. Topyıldız, Ezgi, Handan Duman Şenol, Figen Gülen, Esen Demir, and Nihal Mete Gökmen. - Could Age and Oral Challenge Outcomes Identify High-Risk Patients During Cow’s Milk Oral Immunotherapy?
Duman Senol, Handan, Ezgi Topyildiz, Ezgi Ulusoy Severcan, Sanem Eren Akercan, Nursen Cigerci Gunaydin, Figen Gulen, and Esen Demir - Effectiveness and adverse reactions to subcutaneous immunotherapy in children with allergic rhinitis/asthma.
International Journal of Pediatric Otorhinolaryngology 162 (2022): 111292 Senol, Handan Duman, Ezgi Topyildiz, Betul Ekici, Figen Gulen, and Esen Demir.


