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Prof. Rezan Topaloğlu, MD Pediatric Nephrology · Acibadem Atasehir Hospital, İstanbul

Prof. Rezan Topaloğlu, MD

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Pediatric Nephrology · Acibadem Atasehir Hospital, İstanbul

Prof. Rezan Topaloğlu, MD

Prof. Rezan Topaloğlu, MD is a pediatric nephrologist and pediatric rheumatologist at Acibadem Atasehir Hospital in İstanbul, Turkey. She treats children with recurrent urinary tract infections, urinary incontinence, chronic kidney disease, kidney failure, nephrotic syndrome and kidney stone disease. She speaks Turkish and English and offers video consultations to international patients.

Medically verified profile 46+ years in medicineTurkish · EnglishVideo consultation available
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Prof. Rezan Topaloğlu, MDAccepting international patients
SpecialtyPediatric Nephrology
ConsultationVideo · In person · Second opinion
Profile

About Prof. Rezan Topaloğlu, MD

Prof. Rezan Topaloğlu, MD is a pediatric nephrologist with a subspecialty in pediatric rheumatology who sees patients at Acibadem Atasehir Hospital in İstanbul. She graduated from Hacettepe University Faculty of Medicine in 1980 and completed specialty training in pediatrics in the Hacettepe Faculty of Medicine Department of Pediatrics between 1980 and 1984. After compulsory service in pediatrics at Samsun State Hospital from 1986 to 1988, she completed her pediatric nephrology training at Hacettepe University Faculty of Medicine in 1991 and obtained the Medical Specialty Board qualification in Pediatric Rheumatology in 2011. She has more than 46 years in medicine.

Dr. Topaloğlu was a faculty member of the Hacettepe Faculty of Medicine, Departments of Pediatric Nephrology and Rheumatology, from 1988 to 2023, progressing from lecturer (1988) to associate professor (1991) and professor (1999). From 2003 to 2012 she served as professor representative on the Faculty Board and Faculty Executive Board and as International Socrates Erasmus Faculty of Medicine Coordinator. Her training abroad included a period at Foothills Hospital, Calgary, Canada (1984–1985); a TUBİTAK NATO scholarship at London Guys and Hammersmith Hospitals, London, England (1994–1995), working on chronic renal failure, transplantation and systemic lupus erythematosus; and work on Bartter Syndrome at NIH, Washington DC, United States of America (1999–2000). She was elected President of ESPN (European Society for Paediatric Nephrology) for 2019–2022 and has chaired the IPNA (International Pediatric Nephrology Association) World Young Nephrologists Education Committee since 2014. She has 341 publications and studies in international journals, cited 7,751 times, with an H-index of 41. Her memberships include IPNA, ESPN, the European Renal Association (ERA), the Pediatric Rheumatology Association, the Pediatric Nephrology Association (ÇND) and the Turkish Nephrology Association (TND). She joined Acıbadem Healthcare Services in 2023.

Clinical focus

Dr. Topaloğlu evaluates and manages kidney and urinary tract conditions in children. Her areas of expertise include recurrent urinary tract infections in children, urinary incontinence in children, and kidney stone disease in children. She also follows children with chronic kidney disease and kidney failure, as well as nephrotic syndrome. Her published work covers topics such as nephrotic syndrome in children, cystinosis, lupus nephritis, primary hyperoxaluria, distal renal tubular acidosis and pediatric kidney transplantation.

Because of her training in both pediatric nephrology and pediatric rheumatology, she is able to assess children whose kidney findings may be related to an underlying rheumatologic or systemic condition, such as lupus, and to coordinate the diagnostic approach accordingly.

How Dr. Topaloğlu works with international patients

Dr. Topaloğlu speaks Turkish and English, and interpreters can be arranged for other languages. The international patient team coordinates the collection of prior medical reports and imaging, arranges appointments and organizes the hospital visit. A first consultation typically covers the child’s history and symptoms, a review of existing imaging, laboratory results and previous treatments, a clinical examination and a discussion of the possible options. Video consultation is available for international patients who wish to discuss their child’s case before or instead of traveling.

Clinical focus

What Dr. Topaloğlu treats and performs

Each item opens the condition or treatment page with the care pathway for international patients.

Areas of practicePediatric rheumatology

Background

Education, career and memberships

Education & training

Education

  • 2011Medical Specialty Board, Pediatric Rheumatology
  • 1999–2000Worked on Bartter Syndrome at NIH, Washington DC, United States of America.
  • 1999Hacettepe University Faculty of Medicine / Pediatri Professorü
  • 1994–1995Received a TUBİTAK NATO scholarship and worked on chronic renal failure, transplantation and systemic lupus erythematosus at London Guys and Hammersmith Hospitals, London, England.
  • 1991Hacettepe University Faculty of Medicine, Pediatric Nephrology
  • 1991Hacettepe University Faculty of Medicine / Pediatri Associate Professori
  • 1988Hacettepe University Faculty of Medicine / Department of Pediatrics / Lecturer
  • 1984–1985Worked at Foothills Hospital, Calgary, Canada.
  • 1984Hacettepe University Faculty of Medicine, Pediatrics and Diseases
  • 1980Hacettepe University Faculty of Medicine
Career

Professional Experience

  • 2023Acıbadem Healthcare Services
  • 2019–2022Elected President of ESPN (European Society for Paediatric Nephrology)
  • 2014IPNA (International Pediatric Nephrology Association) World Young Nephrologists Education Committee Chair / Present
  • 2003–2012Hacettepe University Faculty of Medicine Professor Representative, Faculty Board and Faculty Executive Board Membership, International Socrates Erasmus Faculty of Medicine Coordinator
  • 1988–2023Hacettepe Faculty of Medicine Faculty Member, Departments of Pediatric Nephrology and Rheumatology
  • 1986–1988Samsun State Hospital / Pediatrics and Diseases / Compulsory Service
  • 1980–1984Hacettepe Faculty of Medicine Department of Pediatrics specialty training
  • Has 341 publications and studies published in international journals. These studies have been cited 7751 times. H-index 41
Memberships

Professional Memberships

  • International Pediatric Nephrology Association (IPNA)
  • European Society for Paediatric Nephrology (ESPN)
  • European Renal Association (ERA)
  • Pediatric Rheumatology Association
  • Pediatric Nephrology Association (ÇND)
  • Turkish Nephrology Association (TND)
Selected publications

Selected Publications

  • Emulation of the control cohort of a randomized controlled trial in pediatric kidney transplantation with Real-World Data from the CERTAIN Registry. Pediatr Nephrol. 2023 May;38(5):1621-1632. doi: 10.1007/s00467-022-05777-x. Epub 2022 Oct 20. PMID: 36264431 Patry C, Sauer LD, Sander A, Krupka K, Fichtner A, Brezinski J, Geissbühler Y, Aubrun E, Grinienko A, Strologo LD, Haffner D, Oh J, Grenda R, Pape L,
  • Omic Studies on In Vitro Cystinosis Model: siRNA-Mediated CTNS Gene Silencing in HK-2 Cells. Lab Invest. 2023 Nov 9;104(1):100287. doi: 10.1016/j.labinv.2023.100287. Online ahead of print. PMID: 37949358 Baysal I, Yabanoglu-Ciftci S, Nemutlu E, Eylem CC, Gok-Topak ED, Ulubayram K, Kir S, Gulhan B, Ucar G, Ozaltin F, Topaloglu R.
  • Determinants of Kidney Failure in Primary Hyperoxaluria Type 1: Findings of the European Hyperoxaluria Consortium. Kidney Int Rep. 2023 Aug 4;8(10):2029-2042. doi: 10.1016/j.ekir.2023.07.025. eCollection 2023 Oct. PMID: 37849991 Metry EL, Garrelfs SF, Deesker LJ, Acquaviva C, D”Ambrosio V, Bacchetta J, Beck BB, Cochat P, Collard L, Hogan J, Ferraro PM, Franssen CFM, Harambat J
  • Long-term renal survival of paediatric patients with lupus nephritis. Nephrol Dial Transplant. 2022 May 25;37(6):1069-1077. doi: 10.1093/ndt/gfab152. PMID: 33826705 Demir S, Gülhan B, Özen S, Çeleğen K, Batu ED, Taş N, Orhan D, Bilginer Y, Düzova A, Ozaltin F, Topaloğlu R.
  • Distal renal tubular acidosis: ERKNet/ESPN clinical practice points. Nephrol Dial Transplant. 2021 Aug 27;36(9):1585-1596. doi: 10.1093/ndt/gfab171. PMID: 33914889 Trepiccione F, Walsh SB, Ariceta G, Boyer O, Emma F, Camilla R, Ferraro PM, Haffner D, Konrad M, Levtchenko E, Lopez-Garcia SC, Santos F, Stabouli S,
  • Rituximab for Children With Difficult-to-Treat Nephrotic Syndrome: Its Effects on Disease Progression and Growth. Front Pediatr. 2019 Jul 30;7:313. doi: 10.3389/fped.2019.00313. eCollection 2019. PMID: 31417883 Topaloglu R, Gülhan B, Çelegen K, İnözü M, Hayran M, Düzova A, Ozaltin F.
  • The Clinical and Mutational Spectrum of Turkish Patients with Cystinosis. Clin J Am Soc Nephrol. 2017 Oct 6;12(10):1634-1641. doi: 10.2215/CJN.00180117. Epub 2017 Aug 9. PMID: 28793998 Topaloglu R, Gulhan B, Inözü M, Canpolat N, Yilmaz A, Noyan A, Dursun İ, Gökçe İ, Gürgöze MK, Akinci N, Baskin E, Serdaroğlu E, Demircioğlu Kiliç B,
  • Genetic basis of cystinosis in Turkish patients: a single-center experience. Pediatr Nephrol. 2012 Jan;27(1):115-21. doi: 10.1007/s00467-011-1942-6. Epub 2011 Jul 24. PMID: 21786142 Topaloglu R, Vilboux T, Coskun T, Ozaltin F, Tinloy B, Gunay-Aygun M, Bakkaloglu A, Besbas N, van den Heuvel L, Kleta R, Gahl WA
  • A candidate gene for familial Mediterranean fever. Nat Genet. 1997 Sep;17(1):25-31. doi: 10.1038/ng0997-25. PMID: 9288094 A Bernot, C Clepet, C Dasilva, C Devaud, J L Petit, C Caloustian, C Cruaud, D Samson, F Pulcini, J Weissenbach, R Heilig, C Notanicola, C Domingo, M R
  • Molecular basis of hereditary C1q deficiency associated with SLE and IgA nephropathy in a Turkish family. Kidney Int. 1996 Aug;50(2):635-42. doi: 10.1038/ki.1996.359. Topaloglu R, Bakkaloglu A, Slingsby JH, Mihatsch MJ, Pascual M, Norsworthy P, Morley BJ, Saatci U, Schifferli JA, Walport MJ.
Good to Know

Frequently Asked Questions

Which kidney conditions in children does Dr. Topaloğlu treat?
Dr. Topaloğlu evaluates and manages recurrent urinary tract infections, urinary incontinence, chronic kidney disease, kidney failure, nephrotic syndrome and kidney stone disease in children. With training in both pediatric nephrology and pediatric rheumatology, she also assesses children whose kidney involvement may be linked to a rheumatologic condition such as lupus.
Where does Dr. Topaloğlu see patients?
Dr. Topaloğlu sees patients at Acibadem Atasehir Hospital in İstanbul, Turkey. She has been part of Acıbadem Healthcare Services since 2023, after serving as a faculty member of the Hacettepe Faculty of Medicine, Departments of Pediatric Nephrology and Rheumatology, from 1988 to 2023.
What languages does Dr. Topaloğlu speak?
Dr. Topaloğlu speaks Turkish and English. For families who speak other languages, interpreters can be arranged through the international patient team so that the consultation, the review of previous reports and the discussion of options can take place in a language the family understands.
What should we send for a review of our child's case?
It is generally helpful to send existing medical reports, laboratory results, imaging studies and details of previous treatments. The international patient team coordinates the collection of these documents before the appointment so that the first consultation can include a review of the history, findings and prior care.
Does Dr. Topaloğlu offer video consultations for international patients?
Yes. Video consultation is available for international patients. It can be used to discuss a child's history, review existing reports and imaging, and talk through possible next steps before deciding whether a hospital visit is needed. Appointments are coordinated by the international patient team.
What are the highlights of Dr. Topaloğlu's training and professional roles?
Dr. Topaloğlu graduated from Hacettepe University Faculty of Medicine in 1980 and trained in pediatrics and pediatric nephrology there. She worked at Foothills Hospital in Calgary, London Guys and Hammersmith Hospitals, and NIH in Washington DC. She served as elected President of ESPN (European Society for Paediatric Nephrology) from 2019 to 2022.
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