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How a Kidney Transplant Is Performed: Where the New Kidney Goes and What Happens to the Old

28 min read
How a Kidney Transplant Is Performed: Where the New Kidney Goes and What Happens to the Old

Key Takeaways

  • The new kidney is placed in the pelvis, just above the groin, where it can be sewn to the iliac blood vessels and connected easily to the bladder.
  • Your own kidneys are normally left in place; removal is reserved for specific problems such as very large polycystic kidneys, recurrent infection or suspected cancer.
  • The NHS puts the operation at around three hours and Mayo Clinic at three to four, with a hospital stay of about a week for most people.
  • A transplanted kidney may begin working on the operating table or take days to weeks; temporary dialysis during a slow start is common and does not mean failure.
  • Anti-rejection medicines are most intense in the first months and are usually lightened over the first year, but any adjustment must come from the prescribing team.
  • Early rejection often has no symptoms, which is why scheduled blood tests continue even when you feel completely well.
Quick Answer

A kidney transplant is performed under general anesthesia through an incision in the lower abdomen. The surgeon places the donated kidney in the pelvis, just above the groin, joins its artery and vein to nearby blood vessels and connects its ureter to the bladder. The person's own kidneys are usually left in place unless they are causing problems. The operation typically takes about three to four hours.

The night before surgery, a woman sits on the edge of a hospital bed and asks the resident a question she has been saving for months: “So where, exactly, are you going to put it?” She has pictured the operation a hundred times, and in every version the surgeon lifts out a failed kidney and slides a new one into the empty space. The resident smiles, because almost everyone assumes this. Almost everyone is wrong.

If you have been asking how is a kidney transplant performed, you are probably at a similar point: on a waiting list, or watching a family member move toward one, or weighing a living donation. The details matter here, because the real operation is more elegant, and in some ways gentler, than the imagined one.

This explainer walks through the whole day: the incision, the placement, the connections, what happens to the old kidneys, and what the first weeks usually feel like. Every figure is tied to a mainstream medical source, and every decision, as always, belongs with your transplant team.

How is a kidney transplant performed? The operation in plain language

Strip away the jargon and the procedure has four movements. The surgeon makes an opening, creates a home for the new kidney, plumbs it in, and closes up.

You are asleep throughout. A general anesthetic means medicines keep you fully unconscious and pain-free while a specialist monitors your breathing and heart. Once you are under, the team cleans the skin and makes an incision low on one side of the abdomen, roughly where a trouser pocket sits. According to the NHS, the surgeon then places the donated kidney in this lower abdominal space rather than where your own kidneys sit higher in the back.

Three connections follow, and they are the heart of the operation. The kidney’s artery is sewn to a large artery in the pelvis so blood can flow in. Its vein is sewn to the neighboring vein so filtered blood can flow back out. Finally the ureter, the thin tube that carries urine away from a kidney, is stitched into the bladder. When the surgeon releases the clamps, the pale kidney typically flushes pink within seconds as your blood enters it. Some kidneys begin making urine on the table; others take longer, which we cover later.

The surgeon checks for bleeding, may leave a small drain and a temporary internal stent in the ureter, and closes the wound in layers. A urinary catheter, a soft tube draining the bladder, is usually in place when you wake. Mayo Clinic notes the whole process typically takes about three to four hours.

That is the operation. Everything else in this article is context: why the kidney goes where it goes, what stays behind, and how the body and its new organ negotiate a working relationship.

Where is the new kidney placed, and why not in the usual spot?

Your two native kidneys sit deep in the back, tucked under the ribs on either side of the spine. Reaching them means going through or around thick muscle, and they are surrounded by other organs. The transplant surgeon avoids that neighborhood altogether.

The new kidney goes into the iliac fossa, a natural shallow basin inside the pelvis on the right or left side, just above the groin. Both the NHS and Mayo Clinic describe this lower abdominal placement as standard. The reasons are practical rather than mysterious.

  • Blood supply is right there. The iliac artery and vein run through the pelvis on their way to the leg. They are large, accessible and easy to sew onto.
  • The bladder is close. A donated kidney comes with only a short length of ureter, and the pelvis puts that ureter within easy reach of the bladder wall.
  • Access is simpler. A single incision in the lower abdomen reaches the space without cutting through major muscle groups or entering the abdominal cavity itself, which generally means less disruption and an easier recovery.
  • Monitoring is easier afterward. A kidney near the surface can be felt through the skin and scanned with ultrasound in minutes, so problems can be spotted quickly.

Which side is chosen depends on your anatomy, previous surgeries, the quality of the blood vessels on each side and sometimes which kidney the donor gave. A right donor kidney is often placed on the left and vice versa, because flipping it lines the vessels up more neatly with the bladder in front. Your surgeon may mark the planned side before you go to sleep.

The result is a kidney you can sometimes feel as a firm, smooth bulge low on one side. Many recipients find this strange at first and reassuring later: a daily, tangible reminder that the organ is there and working.

What happens to the old kidneys after a transplant?

Here is the answer that surprises the woman on the hospital bed: usually, nothing. The NHS is clear that a person’s own kidneys are normally left in place unless they are causing problems. After a standard transplant you have three kidneys, two quiet and one working.

Removing a kidney is a substantial operation in its own right. It adds surgical time, blood loss and recovery, and in most people it brings no benefit. Failed kidneys shrink, sit harmlessly in the back and, in some cases, keep producing a small volume of urine and certain hormones. Leaving them alone is the safer default.

Surgeons do recommend taking one or both out in specific situations, a procedure called a native nephrectomy. Cleveland Clinic and the NHS describe the usual triggers:

  • Very large polycystic kidneys that leave no room in the pelvis or cause pain and pressure.
  • Repeated kidney infections that could seed infection into a newly transplanted, immunosuppressed body.
  • Blood pressure that stays dangerously high despite treatment and appears to be driven by the diseased kidneys.
  • Suspected or confirmed cancer in a native kidney.
  • Severe reflux, where urine flows backward toward the kidneys, or large stones causing recurrent trouble.

When removal is needed, the timing varies. Sometimes it is done months before the transplant so the person has healed fully by surgery day. Sometimes it happens during the same operation. Occasionally it is deferred until after the new kidney is stable. Each approach carries trade-offs that your team will weigh against your specific anatomy and history.

A related question comes up often: does the old kidney interfere with the new one? It does not. The transplanted kidney has its own blood supply and its own route to the bladder. The native kidneys neither compete with it nor “confuse” the body.

Who is a kidney transplant usually for, and who is asked to wait

Transplant is one of two long-term treatments for kidney failure; dialysis is the other. The NHS describes transplant as the treatment of choice for most people with end-stage kidney disease, meaning kidney function has fallen so far that it cannot sustain life without help. Some people are assessed and listed before they ever start dialysis, an approach known as pre-emptive transplantation.

Being suitable is less about age and more about whether your body can safely tolerate a major operation and the medicines that follow. Assessment typically involves heart tests, imaging, blood work, infection screening, blood group and tissue typing, and conversations with a surgeon, a nephrologist, a pharmacist and often a psychologist or social worker.

The NHS and Mayo Clinic describe circumstances in which a team may advise delaying or not listing:

  • An active infection, which immunosuppression could make far worse.
  • Cancer that is still being treated or was treated very recently; many centers require a disease-free interval.
  • Heart or lung disease severe enough that the anesthetic itself would be unsafe, or that the person is unlikely to live long enough to benefit.
  • Ongoing alcohol or drug dependence that has not yet been addressed with support.
  • A situation that would make it very hard to take medicines reliably every day, since a transplanted kidney depends on them.

Being asked to wait is not the same as being turned away. Someone with a high body weight, for instance, may be supported to lose some before listing because the operation and wound healing are technically safer; the goal is to make surgery possible, not to judge. Someone with a treatable heart problem may have that fixed first.

Your team’s job is to be honest about what would make the transplant more likely to succeed for you. Ask them directly what, if anything, stands between you and the list, and what the plan is to get there.

How is a kidney transplant performed differently with a living donor?

The operation on the recipient is essentially the same whichever kidney arrives. What changes is the timing, the preparation and the condition of the organ.

A deceased donor kidney comes with a phone call. The NHS notes that the average wait for such a kidney is two to three years, and when one becomes available you may have only hours to reach the hospital. Blood tests are repeated to confirm compatibility, you are examined for any infection or new problem, and if everything lines up, surgery follows quickly, often that same day or night. The kidney has been kept cold in a preservation solution, and time out of a body matters, so there is a sense of urgency.

A living donor kidney is scheduled. Donor and recipient are usually in adjoining operating rooms. The donor’s kidney is most often removed through several small keyhole incisions using a camera, a laparoscopic nephrectomy, and it passes straight to the recipient’s surgeon with almost no cold storage time. Mayo Clinic notes that living donor kidneys can be transplanted with less waiting and may function sooner because the organ spends minimal time without blood flow.

Aspect Living donor Deceased donor
Timing Planned date Short notice, often within hours
Typical wait Weeks to months, depending on donor workup Averages two to three years (NHS)
Kidney storage time Minutes Hours, kept cold
Chance of immediate function Higher (Mayo Clinic) Delayed function more common
Recipient operation Same technique Same technique

Living donation involves a healthy person having surgery, and donor safety is protected by its own independent assessment. If a relative or friend offers, they will be evaluated by a team whose sole loyalty is to them. That separation is deliberate and worth respecting.

Kidney transplant surgery steps: what happens in the operating room

Recipients rarely remember anything past the anesthetic room, so here is the sequence the team follows once you are asleep. It is drawn from descriptions published by the NHS, Mayo Clinic and Cleveland Clinic.

Step What the surgeon does Why it matters
1. Preparation Inserts a bladder catheter, positions you, cleans and drapes the abdomen The catheter lets the team measure urine minute by minute once the kidney is connected
2. Incision Makes a curved cut low on one side of the abdomen Reaches the iliac fossa without entering the abdominal cavity
3. Exposing vessels Frees the iliac artery and vein from surrounding tissue Creates clean surfaces to sew onto
4. Preparing the kidney Trims excess fat, checks the donor vessels and ureter on a cold bench Prevents leaks and ensures a good fit
5. Vein connection Sews the kidney vein to the iliac vein Outflow path for filtered blood
6. Artery connection Sews the kidney artery to the iliac artery Inflow of oxygenated blood
7. Reperfusion Releases the clamps The kidney turns pink and may start producing urine
8. Ureter to bladder Stitches the ureter into the bladder wall, often over a temporary stent Gives urine a route out and protects the join while it heals
9. Closure Checks for bleeding, may place a drain, closes muscle and skin Sets up healing and early monitoring

Reperfusion is the moment surgeons watch most closely. Blood pressure is kept steady so the new kidney is well supplied, and the anesthesia team often gives fluids to encourage early urine output. Those first drops in the catheter bag are a good sign, but their absence is not a verdict; many healthy kidneys need time.

The ureteric stent, a soft plastic tube inside the ureter, is removed later in a brief outpatient procedure once the join has healed. You will be told when that is planned before you leave hospital.

How long does kidney transplant surgery take?

The honest answer has two parts: the time the surgeon spends operating, and the time you are away from your family.

The NHS puts the operation itself at around three hours. Mayo Clinic gives a range of about three to four hours. Those figures cover incision to closure for a straightforward first transplant.

Several things stretch the timeline without meaning anything has gone wrong. Scar tissue from previous abdominal or pelvic surgery slows the dissection. Blood vessels hardened by years of high blood pressure or diabetes need more careful handling. A donor kidney with two arteries instead of one requires an extra connection. A native nephrectomy performed in the same sitting adds substantial time. Second and third transplants are generally longer than first ones because the easiest site may already be occupied.

Then there is everything around the operation. Anesthetic induction and line placement happen before the first cut. After closure you spend time in a recovery unit while you wake and your breathing, blood pressure and urine output are checked. From the moment you say goodbye to the moment your family sees you again, the total is often considerably longer than the operating time alone. Ask the team for a realistic window so relatives are not alarmed by a long afternoon.

What about the donor? A laparoscopic donor nephrectomy is a separate operation with its own duration, and the recipient’s surgery cannot begin its vascular stage until the kidney arrives. With living donation, the two are choreographed so the kidney spends as little time as possible on ice.

Length of surgery is not a measure of quality or of how well the kidney will do. A longer operation is usually a more complex one, handled deliberately. Your surgeon will explain afterward what they found and how it went.

Waking up: the first 48 hours after a kidney transplant

Most people surface groggy in a recovery area or a transplant unit, aware of a dull ache low on one side and an unfamiliar collection of tubes. Knowing what each one is for makes the scene less alarming.

You will have a catheter draining urine, which the team measures hourly because volume is one of the earliest signals of how the kidney is behaving. There is usually an intravenous line delivering fluids and medicines, sometimes a central line in the neck for larger volumes, a small drain near the wound, and monitoring stickers on your chest. Oxygen by mask or nasal prongs is routine for the first hours.

Blood tests are frequent, often several times in the first day. Creatinine, a waste product the kidney clears, is the number everyone watches; a falling level means the new organ is filtering. An ultrasound of the transplant is typically done early to confirm blood is flowing well through the artery and vein.

Anti-rejection medicines begin immediately, in some protocols during the operation itself. The transplant pharmacist or nurse will start teaching you their names and timing while you are still in bed, because this is knowledge you will use every day for as long as the kidney works.

Getting up matters. Nurses usually help you sit out of bed and take a few steps within the first day, which reduces the risk of chest infection and blood clots in the legs. It feels daunting; it is also one of the most protective things you can do.

Eating and drinking resume gradually. Bowel function can be slow after abdominal surgery and after opioid painkillers, so passing wind is greeted with genuine enthusiasm. The NHS notes that most people stay in hospital for about a week, though this varies with how quickly the kidney and the person recover.

Does the new kidney work straight away? Delayed graft function explained

Some kidneys produce urine before the surgeon has finished closing. Others sit quietly for days. Both can end up working well, and understanding why prevents a great deal of unnecessary fear in that first week.

The NHS explains that a transplanted kidney may start working immediately or may take a few days or even weeks to function. When function is slow to start, clinicians call it delayed graft function. The usual cause is temporary injury from the period the kidney spent without blood flow, especially in deceased donor organs stored for hours before surgery. The filtering cells are stunned rather than dead, and they recover as swelling settles and blood supply stabilizes.

During this period you may need dialysis, sometimes only once or twice, to clear waste and fluid while the kidney wakes. Your team will monitor creatinine, urine volume and ultrasound findings and will often perform a small biopsy, taking a sliver of kidney tissue with a needle, if recovery is slower than expected. The biopsy is looking for two things: whether the delay is simple injury that will heal, or whether early rejection or a problem with a blood vessel is contributing.

Living donor kidneys, which spend only minutes between donor and recipient, are less likely to experience this delay, as Mayo Clinic notes. That is one of several reasons transplant teams value living donation when it is available.

How people experience this varies. A recipient whose catheter bag fills steadily from hour one often feels an almost giddy relief. A recipient who needs dialysis on day three can feel the operation has failed. It usually has not. Ask your team what they are seeing on tests and what pattern they expect. A slow start is a known chapter in many transplant stories, not a rewrite of the ending.

How painful is a kidney transplant?

This is one of the most searched questions about the procedure, and it deserves a straight answer: there is pain, it is manageable, and for most people it is less than they braced for.

The incision sits in the lower abdomen and, importantly, does not cut through the large muscles of the back or open the main abdominal cavity. Mayo Clinic describes soreness and pain around the incision site as expected during healing. Recipients often compare it to a deep bruise that hurts when they cough, laugh, twist or get out of a chair, and eases when still.

Pain control begins before you wake. Anesthesia teams commonly combine several approaches: local anesthetic around the wound, sometimes a nerve block that numbs the area, and regular painkillers of different classes so no single one has to do all the work. Many units use a patient-controlled pump for the first day or two, which lets you deliver a preset dose by pressing a button with built-in safety limits. Which medicines are used, and for how long, is decided by your team based on your kidney function, other conditions and how you respond.

Nurses will ask you to score your pain regularly. Be candid. Under-reporting pain to seem stoic tends to backfire, because uncontrolled pain makes it harder to breathe deeply, walk and sleep, all of which slow recovery.

Two other discomforts surprise people more than the wound. The bladder catheter can cause a cramping urge to urinate even though the bladder is draining, and this settles after removal. Bloating and trapped wind from a sluggish bowel can ache more than the incision for a day or two; walking helps.

By the time most people go home, pain has usually shifted from needing strong medicines to needing simpler ones, and the wound is more of a nuisance than a torment.

How serious is a kidney transplant? Risks in neutral terms

A kidney transplant is major surgery performed on people whose bodies have already been strained by kidney failure. It deserves respect. It is also a mature, standardized operation with well-characterized risks, and transplant teams spend much of their energy anticipating them.

The NHS groups the risks into short-term surgical complications and longer-term issues linked to immunosuppression. In the early period these include:

  • Bleeding, occasionally requiring transfusion or a return to the operating room.
  • Blood clots in the kidney’s artery or vein, a rare but urgent problem that can threaten the organ.
  • Narrowing of the artery feeding the kidney, which can develop weeks or months later and raise blood pressure.
  • Leakage or blockage of the ureter where it joins the bladder.
  • Wound infection or a collection of fluid around the kidney.
  • Rejection, where the immune system recognizes the kidney as foreign and attacks it. Acute rejection is most common in the first months and is often treatable if caught early, which is why blood tests are so frequent.

Longer term, the medicines that protect the kidney also carry a price. The NHS lists a higher risk of infections, of new-onset diabetes, of high blood pressure and raised cholesterol, and of certain cancers, particularly skin cancer, which is why sun protection and skin checks become lifelong habits.

Set against all of this is the alternative. Long-term dialysis carries its own serious risks and a heavy daily burden. The NHS states that most people with kidney failure who are fit for surgery are better served by transplant than by remaining on dialysis, which is why it is offered so widely.

How serious the operation is for you specifically depends on your heart, your lungs, your age, your other conditions and your kidney’s source. This is exactly what the assessment process is designed to measure, and your team should be able to walk you through your own risk profile in plain terms.

How anti-rejection medicines work, and why timing matters more than most people expect

Your immune system is superb at recognizing cells that do not belong to you. Ordinarily that protects you from infection. After a transplant it becomes the main threat to the new kidney, and lifelong medication is the way that threat is held in check.

Immunosuppressants, medicines that dampen immune activity, are usually given in combination so that several different pathways are blocked at once and each medicine can be used at a lower intensity. The NHS describes three broad groups that are commonly combined. Calcineurin inhibitors, such as the generic tacrolimus, quiet the signaling that activates T cells, the immune cells that lead rejection. Antiproliferative agents slow the multiplication of immune cells. Corticosteroids broadly reduce inflammation and immune response. Some protocols also give a short course of a powerful antibody treatment around the time of surgery, called induction, to blunt the immune system’s first reaction.

Timing follows a typical arc. The most intense suppression is in the first weeks and months, when rejection risk is highest. Over the first year the regimen is usually simplified and lightened as the immune system settles into an uneasy truce. Blood levels of some medicines are checked regularly, because too little invites rejection while too much invites infection and side effects; the window is narrow and personal.

The single most important thing you control is consistency. Missing doses, taking them at erratic times, or adding over-the-counter remedies or supplements without checking can shift blood levels enough to matter. Grapefruit and some herbal products, for example, interfere with how certain immunosuppressants are processed. Always ask your transplant pharmacist before starting anything new.

What you should not do is adjust anything yourself. If side effects trouble you, tell the team; there are often alternatives and adjustments. Every change belongs to the prescriber, made with your blood results in front of them.

What the following weeks usually look like: a kidney transplant recovery timeline

Recovery from a transplant runs on two clocks. The wound heals on the familiar schedule of any abdominal operation. The kidney and the immune system settle on a slower, less predictable one. Both are watched intensely.

The NHS reports that most people leave hospital after around a week. Going home does not mean going quiet. Clinic visits are frequent at first, often two or three times a week in the early period, each with blood tests to track creatinine, medicine levels and blood counts. Visits thin out as results stabilize, but for the first few months you should expect to know your hospital’s parking lot well.

Physically, Mayo Clinic advises that most people can return to work and normal activities within about eight weeks. Until the wound has fully knitted, heavy lifting and strenuous core exercise are avoided; Mayo suggests not lifting objects heavier than about ten pounds in this period. Walking is encouraged from day one and can be built up steadily. Driving usually waits until you are off strong painkillers, can brake sharply without pain and your team agrees.

Expect some things to feel odd. The transplanted kidney may be tender to touch. You may urinate more often and in larger volumes than you have in years, which is a good problem. Appetite often returns with surprising force once dialysis dietary restrictions ease, though your dietitian will explain which limits remain.

Emotionally, the weeks after transplant are frequently a mix of gratitude, anxiety about every blood result and a strange grief for the dialysis routine that structured life. All of this is normal and worth naming with your team or a counselor.

The NHS also gives a sense of the longer arc: kidneys from deceased donors last on average around ten to twelve years, and those from living donors around fifteen to twenty. These are averages, not promises, and many work far longer.

What people often get wrong about how a kidney transplant is performed

Some misconceptions are harmless. Others cause real distress or lead people to delay listing. Here are the ones transplant nurses hear most.

“They swap the old kidney for the new one.” The new kidney goes in the pelvis, and the old kidneys stay in the back unless there is a specific medical reason to remove them, as the NHS explains. Most recipients live with three kidneys.

“If it doesn’t work immediately, the transplant has failed.” Delayed graft function, where the kidney takes days or weeks to start, is a recognized pattern, particularly with deceased donor organs. Temporary dialysis during this window is a bridge, not a verdict.

“A transplant is a one-time fix.” A kidney transplant is a treatment for kidney failure, not an end to it. The organ needs lifelong medicines and monitoring, and it may eventually stop working, at which point dialysis or a second transplant become options again.

“Older people can’t have transplants.” There is no fixed age limit in NHS guidance. Suitability rests on overall fitness for surgery and medication, which is assessed individually.

“You have to match perfectly.” Blood group and tissue compatibility matter, but modern immunosuppression and paired-exchange schemes, where incompatible donor-recipient pairs swap with other pairs, have widened what is possible. Your team can explain your options.

“The donor is left with a weak kidney.” Living donors undergo rigorous assessment precisely to confirm that one remaining kidney will serve them well. Donation is only approved when that is expected.

“Once you feel well, you can ease off the medicines.” Feeling well is the medicines working. Rejection often has no symptoms in its early stages, which is why the blood tests continue even when you feel fine, and why any change must come from the prescribing team.

Questions to ask your care team before a kidney transplant

A good transplant consultation is a conversation, and the most useful questions are specific to you. Take this list, cross out what does not apply and add your own.

  • Which side do you plan to place the kidney, and is there anything about my anatomy that changes the usual approach?
  • Will my own kidneys stay? If you recommend removing one, why, and when would that happen relative to the transplant?
  • What is the realistic total time I will be away from my family on the day, including anesthesia and recovery?
  • How will pain be managed in the first days, and what is the plan if the usual approach does not suit my kidney function or other conditions?
  • If the kidney is slow to start, what will you do, and how will you tell the difference between delayed function and rejection?
  • Which anti-rejection medicines will I start on, how do they work, and what side effects should I report straight away?
  • What foods, supplements or over-the-counter products should I avoid because they interact with my medicines?
  • How often will I need clinic visits and blood tests in the first three months, and how does that change over the first year?
  • When can I expect to drive, return to work, exercise and travel, based on my situation?
  • What are the signs of infection, rejection or a problem with the wound that mean I should contact you the same day?
  • Who do I call out of hours, and what number?
  • If this kidney eventually stops working, what are the options then?

Write the answers down or bring someone who will. Most people absorb a fraction of what is said in a transplant clinic, and the details matter for months afterward. If an answer is unclear, say so. Teams would far rather explain twice than have you guess.

When to call your doctor after a kidney transplant

After a transplant your body has less capacity to fight infection and less margin to signal trouble. Problems caught early are usually far easier to treat, so transplant teams want to hear from you sooner rather than later. Every unit gives recipients a direct number for exactly this purpose; keep it on your phone and by the front door.

Contact your transplant team the same day, or seek urgent care, if you notice any of the following, which the NHS and Mayo Clinic list as warning signs:

  • A fever, chills or feeling generally unwell in a way you cannot explain.
  • Pain, swelling, redness or tenderness over the transplanted kidney or around the wound.
  • Redness, warmth, discharge or opening of the wound edges.
  • Passing much less urine than usual, or none at all.
  • Blood in the urine, or urine that is cloudy or foul-smelling with burning when you pass it.
  • Rapid weight gain or new swelling of the ankles, legs or face, which can signal fluid building up.
  • Shortness of breath, chest pain or coughing up blood.
  • Pain, swelling or redness in one calf, which can indicate a blood clot.
  • Vomiting or diarrhea that stops you keeping medicines down, since missed doses raise rejection risk.
  • A blood pressure reading far above your usual range, if you monitor at home.
  • Any flu-like illness, or contact with someone who has chickenpox, shingles or measles.

Early rejection often produces no symptoms at all, which is why scheduled blood tests remain essential even when you feel entirely well. Never skip them because you feel good.

If something feels wrong and is not on this list, call anyway. Recipients know their bodies, and transplant teams take that seriously. The decision about what to do next always rests with the clinicians who know your kidney, your medicines and your history.

Frequently asked questions

Where is the new kidney placed during a transplant?

The new kidney is placed in the lower abdomen, in a natural hollow of the pelvis called the iliac fossa, just above the groin on the right or left side. Surgeons choose this site because the large iliac artery and vein run through it and the bladder is close by, making the three necessary connections straightforward. It also keeps the kidney near the skin surface, where it is easy to examine and scan.

What happens to your old kidneys after a transplant?

Your own kidneys usually stay where they are. The NHS notes they are left in place unless they are causing problems such as repeated infection, uncontrolled high blood pressure, very large cysts or suspected cancer. Removing them is a significant extra operation with no benefit for most people. After a standard transplant you therefore have three kidneys: two failed ones in the back and one working one in the pelvis.

How long does kidney transplant surgery take?

The operation itself typically takes about three hours according to the NHS, or three to four hours according to Mayo Clinic. Time in the anesthetic room beforehand and the recovery unit afterward adds to the total, so relatives should expect a longer wait. Previous abdominal surgery, hardened blood vessels, a donor kidney with extra arteries or removal of a native kidney in the same sitting can all lengthen the procedure.

How painful is a kidney transplant?

There is pain, mostly soreness around the lower abdominal incision that worsens with coughing, twisting or standing, but most people describe it as manageable and less than feared. The incision avoids the back muscles and the main abdominal cavity, which helps. Pain is controlled with a combination of approaches chosen by your team, and by discharge most recipients need only simpler painkillers. Report pain honestly so it can be adjusted.

How serious is a kidney transplant?

It is major surgery with real risks, including bleeding, blood clots in the kidney’s vessels, ureter problems, infection and rejection, plus longer-term effects of anti-rejection medicines such as higher infection and skin cancer risk. The NHS nevertheless describes transplant as the preferred treatment for most people with kidney failure who are fit for surgery, because long-term dialysis carries its own serious burdens. Your personal risk depends on your heart, lungs and other conditions, which the assessment measures.

What are the main kidney transplant surgery steps?

Under general anesthesia the surgeon inserts a bladder catheter, makes an incision low on one side of the abdomen, exposes the iliac vessels, prepares the donor kidney, sews its vein and then its artery to those vessels, releases the clamps so blood flows in, and stitches the ureter into the bladder, often over a temporary stent. After checking for bleeding the wound is closed, sometimes with a small drain left in place.

Does the new kidney start working immediately?

Not always. Some kidneys make urine within minutes of blood flow returning; others take days or even weeks, a pattern called delayed graft function that the NHS describes as recognized and usually temporary. It is more common with deceased donor kidneys that have been stored cold for hours. Dialysis may be needed as a bridge during this period, and a biopsy may be done to distinguish slow recovery from early rejection.

How long do you stay in hospital after a kidney transplant?

The NHS reports that most people stay in hospital for around a week after a kidney transplant. The exact length depends on how quickly the kidney starts working, how pain and bowel function settle, and whether any early complications arise. Discharge is followed by frequent clinic visits and blood tests in the first weeks, so leaving hospital marks the start of intensive monitoring rather than the end of care.

How long does it take to recover from a kidney transplant?

Mayo Clinic advises that most people can return to work and normal activities within about eight weeks, with heavy lifting avoided until the wound has fully healed. The immune system settles more slowly, so anti-rejection medicines are most intensive in the first months and clinic visits are frequent for much of the first year. Everyone’s timeline differs, and your team will guide the pace based on your test results.

Can you live a normal life with a transplanted kidney?

Many people return to work, travel, exercise and family life, with the ongoing commitments of daily anti-rejection medicines, regular blood tests, sun protection and prompt attention to infections. The NHS notes that kidneys from deceased donors last on average around ten to twelve years and from living donors around fifteen to twenty, though these are averages and many function far longer. Ongoing partnership with the transplant team is part of the new normal.

References

This article is for general information only and is not a substitute for professional medical advice. Please consult a qualified doctor about your individual situation.

Dr. Şule Eren
Dr. Şule Eren, MD
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Published October 8, 2026
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