Pathology · Acibadem Kent Hospital (Izmir) Prof. Banu Lebe, MD
✓ Medically verified profileProf. Banu Lebe, MD
Prof. Banu Lebe, MD is a pathologist in the Pathology Department at Acibadem Kent Hospital (Izmir) in İzmir, Turkey. Her areas of expertise include malignant melanoma, BRAF V600E- and V600K-mutant melanoma, early melanoma, dysplastic nevi and other melanocytic lesions, PRAME immunohistochemistry, and inflammatory skin diseases such as pyoderma gangrenosum. She speaks Turkish and English.
Accepting international patientsAbout Prof. Banu Lebe, MD
Prof. Banu Lebe, MD is a pathologist at Acibadem Kent Hospital (Izmir), where she works in the Pathology Department. Her practice centers on the laboratory evaluation of tissue and cell samples to support diagnosis and clinical decision-making. Dr. Lebe has more than 33 years in medicine, and much of her published work concerns dermatopathology, particularly the histopathologic assessment of melanocytic lesions and inflammatory skin conditions.
Dr. Lebe graduated from Ankara University Faculty of Medicine in 1993 and completed her Medical Pathology training at Dokuz Eylül University Faculty of Medicine in 1998. She then pursued an academic career at Dokuz Eylül University in the Department of Surgical Medical Sciences, serving as Assistant Professor from 2001 to 2005, Associate Professor from 2005 to 2011, and Professor from 2011. She joined Acıbadem Healthcare Services in 2025. She speaks Turkish and English.
Clinical focus
Dr. Lebe’s areas of expertise include malignant melanoma, with particular attention to BRAF V600E-mutant and BRAF V600K-mutant melanoma, early melanoma, intermediate melanocytic lesions, low-grade dysplastic nevi and melanocytic lesions with peripheral globules. Her published research addresses the diagnostic performance of dermoscopy in distinguishing early melanomas and intermediate melanocytic lesions from low-grade dysplastic nevi, the management of melanocytic lesions with peripheral globules according to the grade of dysplasia, and the clinicopathologic characteristics of BRAF V600K-mutant melanoma compared with V600E-mutant cases. She has also studied PRAME immunohistochemistry, including the relationship of PRAME expression with clinicopathologic parameters and immunologic markers in melanoma, as well as genetic and epigenetic changes in melanoma progression.
Beyond melanocytic pathology, Dr. Lebe has contributed to case reports and studies on inflammatory and infectious skin disease, including febrile ulceronecrotic Mucha-Habermann disease, pyoderma gangrenosum, lupus erythematosus panniculitis and viral exanthema in COVID-19. Her work also extends to human herpesvirus 6-associated panuveitis. As a pathologist, her role is to examine and interpret samples and to report findings that treating dermatologists, surgeons, oncologists and other physicians use when planning care.
How Dr. Lebe works with international patients
Dr. Lebe communicates in Turkish and English, and interpreters can be arranged for patients who speak other languages. For international patients, the Acibadem international patient team coordinates the collection of prior reports and imaging, such as MRI, CT, X-ray or ultrasound reports, laboratory and pathology results, operative notes and discharge summaries, and arranges appointments and the hospital visit. A first consultation typically covers the patient’s history and symptoms, a review of existing imaging and previous treatments, a clinical examination and a discussion of the options. Pathology findings are delivered within a multidisciplinary setting and support the care plans of the treating physicians. Video consultation is available for international patients.
What Dr. Lebe treats and performs
Each item opens the condition or treatment page with the care pathway for international patients.
Conditions treated
- Malignant melanoma
- BRAF v600e-mutant melanoma
- BRAF v600k-mutant melanoma
- Early melanoma
- Intermediate melanocytic lesions
- Low-grade dysplastic nevi
- Melanocytic lesions with peripheral globules
- Febrile ulceronecrotic mucha-habermann disease
Education, career and memberships
Education & training
Education
- 2011Dokuz Eylül University, Faculty of Medicine, Department of Surgical Medical Sciences - Prof. Dr.
- 2005–2011Dokuz Eylül University, Department of Surgical Medical Sciences - Associate Professor
- 2001–2005Dokuz Eylül University, Department of Surgical Medical Sciences - Assistant Professor
- 1998Dokuz Eylül University Faculty of Medicine Medical Pathology
- 1993Ankara University Faculty of Medicine
Career
Professional Experience
- 2025Acıbadem Healthcare Services
Selected publications
Selected Publications
- Human Herpesvirus 6-Associated Unilateral Panuveitis Mimicking Endogenous Endophthalmitis in a Case with Ulcerative Colitis: Report of a Case and Literature Review Ocular Immunology and Inflammation, 2025 (SCI-Expanded) KARTI Ö., AYHAN Z., LEBE B., SAATCİ A. O.
- The Relationship of PRAME Expression with Clinicopathologic Parameters and Immunologic Markers in Melanomas: In Silico Analysis Applied Immunohistochemistry and Molecular Morphology, vol.33, sa.2, pp.117-130, 2025 (SCI-Expanded) Cakir Y., LEBE B.
- Diagnostic Performance of Dermoscopy for Distinguishing Early Melanomas and Intermediate Melanocytic Lesions From Low-Grade Dysplastic Nevi Journal of Cutaneous Medicine and Surgery, 2025 (SCI-Expanded) AVCI C., Kaşıkçı M., LEBE B., AKARSU S., İLKNUR T.
- Genetic and Epigenetic Changes in Melanoma Progression: A TCGA-based Study Applied Immunohistochemistry and Molecular Morphology, vol.33, no.3, pp.170-179, 2025 (SCI-Expanded) ÇAKIR Y., LEBE B., TOPER M., SARIOĞLU S.
- Can we manage the melanocytic lesions with peripheral globules according to the grade of dysplasia? The Australasian journal of dermatology, vol.65, sa.4, pp.358-368, 2024 (SCI-Expanded) Avcı C., Akın G. N., Lebe B., Şahin M. T., Fetil E.
- Febrile ulceronecrotic Mucha-Habermann disease during pregnancy: A case report. The Australasian journal of dermatology, vol.64, sa.2, pp.245-248, 2023 (SCI-Expanded) Avcı C., Gürbüz Ö., Özbağçıvan Ö., Lebe B.
- Pyoderma gangrenosum and Behcet’s-like disease induced by secukinumab: a paradoxical drug reaction. The Journal of dermatological treatment, vol.34, sa.1, pp.2235040, 2023 (SCI-Expanded) Avcı C., Akın G. N., Akarsu S., Lebe B.
- Clinicopathologic characteristics of BRAF V600K mutant malignant melanoma in comparison with V600E mutant cases: a preliminary study VIRCHOWS ARCHIV, vol.481, sa.SUPPL 1, 2022 (SCI-Expanded) Bulbul G., Agalar A. A., Yumuk E., Cagaptay S., Ellidokuz H., Lebe B.
- Exacerbation of lupus erythematosus panniculitis after administration of COVID-19 mRNA vaccine INDIAN JOURNAL OF DERMATOLOGY, vol.67, sa.6, pp.825-828, 2022 (SCI-Expanded) Avcı C., Şirin N. D., İlknur T., Lebe B., Akarsu S.
- Viral exanthema in a COVID-19 patient VIRCHOWS ARCHIV, vol.481, sa.SUPPL 1, 2022 (SCI-Expanded) Yumuk E., Cagaptay S., Bulbul G., Lebe B.
