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Dr. Ezgi Topyıldız Pediatric Allergy

Dr. Ezgi Topyıldız

✓ Medically verified profile
Pediatric Allergy

Dr. Ezgi Topyıldız

✓ Medically verified profile
14+ years experienceLanguages: Turkish, EnglishOnline consultationAcibadem Atasehir Hospital · İstanbul
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Dr. Ezgi Topyıldız
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About Dr. Ezgi Topyıldız

Quick answer

Dr. Ezgi Topyıldız is a Pediatric Allergy specialist at Acibadem Atasehir Hospital in İstanbul with 14+ years of experience.

She treats primary immunodeficiencies and inborn errors of immunity, including common variable immunodeficiency, MHC class II deficiency, transient hypogammaglobulinemia of infancy, unclassified syndromic immunodeficiencies, and autoimmune cytopenias, as well as egg allergy, cow’s milk allergy, allergic rhinitis, pediatric asthma, and hereditary angioedema; she also performs subcutaneous immunotherapy, cow’s milk oral immunotherapy, and subcutaneous…

M.D. Ezgi Topyıldız is a pediatric immunology and allergy specialist trained at Ege University Faculty of Medicine, where she completed her training in Pediatric Immunology and Allergy Diseases in 2022. She currently practices with Acibadem Health Group (since 2024), providing care for children and adolescents with allergic and immunologic conditions. Her clinical interests include primary immunodeficiencies, allergic diseases in childhood, diagnostic immunology, and individualized management plans that blend evidence-based care with family-centered communication. M.D.

Topyıldız is committed to staying current with advances in immunology and allergy through active involvement in professional societies. Professional memberships – European Society for Immunodeficiencies (ESID) – European Academy of Allergy and Clinical Immunology (EAACI) – Turkish National Society of Allergy and Clinical Immunology – Society of Clinical Immunology M.D. Topyıldız is known for her thoughtful approach to complex cases and for working closely with families to improve quality of life for her young patients.

Clinical Focus

Areas of Expertise

Conditions treated and procedures performed by this specialist.

Primary immunodeficienciesCommon variable immunodeficiencyMHC class II deficiencyTransient hypogammaglobulinemia of infancyUnclassified syndromic immunodeficienciesAutoimmune cytopenias in inborn errors of immunityEgg allergyCow's milk allergyAllergic rhinitisPediatric asthmaHereditary angioedemaSubcutaneous immunotherapyCow's milk oral immunotherapySubcutaneous immunoglobulin replacement therapy
Background

Education

  • 2022Ege University Faculty of Medicine Pediatric Immunology and Allergy Diseases
  • 2016Istanbul University Istanbul Faculty of Medicine Pediatrics
  • 2011Istanbul University Cerrahpasa Faculty of Medicine
Career

Professional Experience

  • 2024Acibadem Health Group
  • 2023–2024Hatay Training and Research Hospital
  • 2019–2023Ege University Faculty of Medicine Hospital
  • 2016–2019Ministry of Health University Zeynep Kamil Training and Research Hospital
  • 2012–2016Istanbul University Istanbul Faculty of Medicine
Affiliations

Professional Memberships

  • European Society Immunodeficiencies (ESID)
  • Turkish National Society of Allergy and Clinical Immunology
  • European Academy of Allergy and Clinical Immunology (EAACI)
  • Turkish National Society of Allergy and Clinical Immunology
  • Society of Clinical Immunology
Research

Selected Publications

  • Current genetic defects in common variable immunodeficiency patients on the geography between Europe and Asia: a single-center experience. Immunologic Research 72, no. 2 (2024): 225-233. Aygun, Ayse, Ezgi Topyıldız, Mehmet Geyik, Neslihan Edeer Karaca, Asude Durmaz, Guzide Aksu, Ayca Aykut, and Necil Kutukculer
  • Facilitated Subcutaneous Immunoglobulin Treatment Increases the Quality of Life and Decreases the Number of Infections and Hospitalizations in Children with Primary Immunodeficiencies International Archives of Allergy and Immunology 185, no. 4 (2024): 382-391. Erbaş Açıcı, Nida, Ezgi Topyildiz, Ayşe Aygün, Mehmet Geyik, Neslihan Edeer Karaca, Guzide Aksu, and Necil Kutukculer.
  • MHC Class II Deficiency: Clinical, Immunological, and Genetic Insights in a Large Multicenter Cohort. The Journal of Allergy and Clinical Immunology: In Practice 12, no. 9 (2024): 2490-2502 Koksal, Zeynep Gulec, Sevgi Bilgic Eltan, Ezgi Topyildiz, Ahmet Sezer, Sevgi Keles, Figen Celebi Celik, Aylin Ozhan Kont et al.
  • Autoimmune Cytopenias Are Highly Associated with Inborn Errors of Immunity and They May Be the Initial Presentations in Cases without Severe Infections. International Archives of Allergy and Immunology 185, no. 4 (2024): 392-401. Taskin, Raziye Burcu, Ezgi Topyıldız, Neslihan Edeer Karaca, Guzide Aksu, Deniz Yılmaz Karapınar, and Necil Kutukculer.
  • Factors effecting natural course of egg allergy. Eur Ann Allergy Clin Immunol 56, no. 3 (2024): 116-120. Şenol, Handan Duman, Mehmet Geyik, Ezgi Topyıldız, Ayşe Aygün, Figen Gülen, and Esen Demir.
  • Transient hypogammaglobulinemia of infancy and unclassified syndromic immunodeficiencies are highly common in oesophageal atresia patients. Scandinavian Journal of Immunology 99, no. 2 (2024): e13338. Ulman, Hilmican, Ayşe Aygün, Deniz Çağlar, Zafer Dökümcü, Ezgi Topyıldız, Ata Erdener, Güzide Aksu, Neslihan Edeer Karaca, Coşkun Özcan, and Necil Küt
  • Alterations in B and NK cells highly correlate with disease severity in children with COVID-19. Turkish Journal of Medical Sciences 53, no. 5 (2023): 1205-1213 Topyildiz, Ezgi, Neslihan Karaca, Raziye Burcu Taşkın, Ayşe Aygün, Zümrüt Şahbudak Bal, Eylem Ulaş Saz, Nuri Zafer Kurugöl, Necil Kütükçüler, and Güzi
  • Successful treatment of post-pericardiotomy syndrome via C1 inhibitor replacement therapy in a hereditary angioedema patient with Marfan syndrome. The Turkish Journal of Pediatrics 65, no. 2 (2023): 338-343. Topyıldız, Ezgi, Handan Duman Şenol, Figen Gülen, Esen Demir, and Nihal Mete Gökmen.
  • Could Age and Oral Challenge Outcomes Identify High-Risk Patients During Cow’s Milk Oral Immunotherapy? Duman Senol, Handan, Ezgi Topyildiz, Ezgi Ulusoy Severcan, Sanem Eren Akercan, Nursen Cigerci Gunaydin, Figen Gulen, and Esen Demir
  • Effectiveness and adverse reactions to subcutaneous immunotherapy in children with allergic rhinitis/asthma. International Journal of Pediatric Otorhinolaryngology 162 (2022): 111292 Senol, Handan Duman, Ezgi Topyildiz, Betul Ekici, Figen Gulen, and Esen Demir.
Good to Know

Frequently Asked Questions

What is Dr. Ezgi Topyıldız's specialty?
Dr. Ezgi Topyıldız is a specialist in Pediatric Allergy at Acibadem. For a personalised assessment, the Acibadem international patient team can review your medical history and reports and explain the suitable next steps.
Which hospital does Dr. Ezgi Topyıldız practise at?
Dr. Ezgi Topyıldız sees patients at Acibadem Atasehir Hospital in İstanbul. The international patient team can confirm current availability and help you plan a consultation or visit.
What languages can I use when consulting Dr. Ezgi Topyıldız?
Consultations with Dr. Ezgi Topyıldız are supported in Turkish and English. In addition, Acibadem provides multilingual coordination and interpreter support so international patients can communicate clearly throughout their care.
How can I book an appointment with Dr. Ezgi Topyıldız?
You can request an appointment with Dr. Ezgi Topyıldız using the appointment form on this page, or by contacting the Acibadem international patient team by phone or WhatsApp. After you share your details, the team checks availability and confirms your appointment, usually within 24 hours.
Is an online video consultation available with Dr. Ezgi Topyıldız?
Yes. Dr. Ezgi Topyıldız offers online video consultations, so you can discuss your condition and reports with the specialist before making any travel arrangements. The international patient team can help you schedule a secure video visit.
How many years of experience does Dr. Ezgi Topyıldız have?
Dr. Ezgi Topyıldız has around 14 years of professional experience in Pediatric Allergy. A summary of education, experience and professional memberships is available on this page.
Can international patients arrange treatment with Dr. Ezgi Topyıldız?
Yes. Acibadem supports international patients end to end — from the first consultation and treatment planning through appointment scheduling, interpretation during the stay and follow-up after returning home. Sharing your case for an initial assessment is free of charge.
How do I get a second opinion involving Dr. Ezgi Topyıldız?
You can request an independent review of your diagnosis and proposed treatment. Share your medical reports through the consultation or "Ask a Doctor" form on this site, and the team will arrange a specialist review and explain the available options.
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