Pediatric Allergy · Acibadem Atasehir Hospital, İstanbul Ezgi Topyıldız, MD
✓ Medically verified profileEzgi Topyıldız, MD
Ezgi Topyıldız, MD is a Pediatric Allergy specialist at Acibadem Atasehir Hospital in İstanbul, working within the Pediatrics unit. She cares for children with childhood asthma, food allergies, urticaria (hives), atopic dermatitis, other pediatric allergies and pediatric immune system disorders. She consults in Turkish and English, and video consultations are available for international patients.
Accepting international patientsAbout Ezgi Topyıldız, MD
Ezgi Topyıldız, MD is a Pediatric Allergy specialist at Acibadem Atasehir Hospital in İstanbul, where she works within the Pediatrics unit. With more than 15 years in medicine, she cares for children with asthma, food allergies, urticaria (hives), atopic dermatitis and other allergic conditions, as well as pediatric immune system disorders.
Dr. Topyıldız graduated from İstanbul University Cerrahpaşa Faculty of Medicine in 2011 and completed her Pediatrics training at İstanbul University İstanbul Faculty of Medicine in 2016. In 2022, she completed her training in Pediatric Immunology and Allergy Diseases at Ege University Faculty of Medicine. Her professional experience includes positions at İstanbul University İstanbul Faculty of Medicine (2012–2016), Ministry of Health University Zeynep Kamil Training and Research Hospital (2016–2019), Ege University Faculty of Medicine Hospital (2019–2023) and Hatay Training and Research Hospital (2023–2024), before joining Acıbadem Healthcare Services in 2024. She is a member of the European Society Immunodeficiencies (ESID), the European Academy of Allergy and Clinical Immunology (EAACI), the Turkish National Allergy and Clinical Immunology Association and the Clinical Immunology Association. She has co-authored peer-reviewed publications on topics including genetic defects in common variable immunodeficiency, facilitated subcutaneous immunoglobulin treatment in children with primary immunodeficiencies, MHC class II deficiency, autoimmune cytopenias in inborn errors of immunity, the natural course of egg allergy, cow's milk oral immunotherapy and subcutaneous immunotherapy in children with allergic rhinitis and asthma.
Clinical focus
Dr. Topyıldız evaluates and manages a range of allergic conditions in children. Her areas of expertise include childhood asthma, food allergies in children, urticaria (hives) in children and atopic dermatitis. Because allergic symptoms in children can overlap and change over time, her assessment takes into account the child's history, previous test results and the course of symptoms before treatment options are discussed with the family.
Alongside pediatric allergies, Dr. Topyıldız has a particular focus on pediatric immune system disorders. Her training in Pediatric Immunology and Allergy Diseases and her published work on primary immunodeficiencies reflect this dual interest, which is relevant for children who present with recurrent infections, unusual infection patterns or immune-related findings in addition to, or instead of, typical allergic symptoms.
How Dr. Topyıldız works with international patients
Dr. Topyıldız consults in Turkish and English, and interpreters can be arranged for families who speak other languages. The Acibadem international patient team coordinates the collection of prior reports and imaging, such as laboratory and pathology results, allergy test reports, discharge summaries and any relevant imaging reports, and arranges appointments and the hospital visit. A first consultation typically covers the child's history and symptoms, a review of existing test results and previous treatments, a clinical examination and a discussion of the options. Video consultations are available for international patients who wish to discuss their child's case before deciding whether to travel.
What Dr. Topyıldız treats and performs
Each item opens the condition or treatment page with the care pathway for international patients.
Conditions treated
- Childhood asthma
- Food allergies in children
- Urticaria (hives) in children
- Pediatric immune system disorders
- Pediatric allergies
- Atopic dermatitis
Procedures performed
Education, career and memberships
Education & training
Education
- 2022Ege University Faculty of Medicine Pediatric Immunology and Allergy Diseases
- 2016İstanbul University İstanbul Faculty of Medicine Pediatrics
- 2011İstanbul University Cerrahpaşa Faculty of Medicine
Career
Professional Experience
- 2024Acıbadem Healthcare Services
- 2023–2024Hatay Training and Research Hospital
- 2019–2023Ege University Faculty of Medicine Hospital
- 2016–2019Ministry of Health University Zeynep Kamil Training and Research Hospital
- 2012–2016İstanbul University İstanbul Faculty of Medicine
Memberships
Professional Memberships
- European Society Immunodeficiencies (ESID)
- Turkish National Allergy and Clinical Immunology Association
- European Academy of Allergy and Clinical Immunology (EAACI)
- Turkish National Allergy and Clinical Immunology Association
- Clinical Immunology Association
Selected publications
Selected Publications
- Current genetic defects in common variable immunodeficiency patients on the geography between Europe and Asia: a single-center experience. Immunologic Research 72, no. 2 (2024): 225-233. Aygun, Ayse, Ezgi Topyıldız, Mehmet Geyik, Neslihan Edeer Karaca, Asude Durmaz, Guzide Aksu, Ayca Aykut, and Necil Kutukculer
- Facilitated Subcutaneous Immunoglobulin Treatment Increases the Quality of Life and Decreases the Number of Infections and Hospitalizations in Children with Primary Immunodeficiencies International Archives of Allergy and Immunology 185, no. 4 (2024): 382-391. Erbaş Açıcı, Nida, Ezgi Topyildiz, Ayşe Aygün, Mehmet Geyik, Neslihan Edeer Karaca, Guzide Aksu, and Necil Kutukculer.
- MHC Class II Deficiency: Clinical, Immunological, and Genetic Insights in a Large Multicenter Cohort. The Journal of Allergy and Clinical Immunology: In Practice 12, no. 9 (2024): 2490-2502 Koksal, Zeynep Gulec, Sevgi Bilgic Eltan, Ezgi Topyildiz, Ahmet Sezer, Sevgi Keles, Figen Celebi Celik, Aylin Ozhan Kont et al.
- Autoimmune Cytopenias Are Highly Associated with Inborn Errors of Immunity and They May Be the Initial Presentations in Cases without Severe Infections. International Archives of Allergy and Immunology 185, no. 4 (2024): 392-401. Taskin, Raziye Burcu, Ezgi Topyıldız, Neslihan Edeer Karaca, Guzide Aksu, Deniz Yılmaz Karapınar, and Necil Kutukculer.
- Factors effecting natural course of egg allergy. Eur Ann Allergy Clin Immunol 56, no. 3 (2024): 116-120. Şenol, Handan Duman, Mehmet Geyik, Ezgi Topyıldız, Ayşe Aygün, Figen Gülen, and Esen Demir.
- Transient hypogammaglobulinemia of infancy and unclassified syndromic immunodeficiencies are highly common in oesophageal atresia patients. Scandinavian Journal of Immunology 99, no. 2 (2024): e13338. Ulman, Hilmican, Ayşe Aygün, Deniz Çağlar, Zafer Dökümcü, Ezgi Topyıldız, Ata Erdener, Güzide Aksu, Neslihan Edeer Karaca, Coşkun Özcan, and Necil Küt
- Alterations in B and NK cells highly correlate with disease severity in children with COVID-19. Turkish Journal of Medical Sciences 53, no. 5 (2023): 1205-1213 Topyildiz, Ezgi, Neslihan Karaca, Raziye Burcu Taşkın, Ayşe Aygün, Zümrüt Şahbudak Bal, Eylem Ulaş Saz, Nuri Zafer Kurugöl, Necil Kütükçüler, and Güzi
- Successful treatment of post-pericardiotomy syndrome via C1 inhibitor replacement therapy in a hereditary angioedema patient with Marfan syndrome. The Turkish Journal of Pediatrics 65, no. 2 (2023): 338-343. Topyıldız, Ezgi, Handan Duman Şenol, Figen Gülen, Esen Demir, and Nihal Mete Gökmen.
- Could Age and Oral Challenge Outcomes Identify High-Risk Patients During Cow’s Milk Oral Immunotherapy? Duman Senol, Handan, Ezgi Topyildiz, Ezgi Ulusoy Severcan, Sanem Eren Akercan, Nursen Cigerci Gunaydin, Figen Gulen, and Esen Demir
- Effectiveness and adverse reactions to subcutaneous immunotherapy in children with allergic rhinitis/asthma. International Journal of Pediatric Otorhinolaryngology 162 (2022): 111292 Senol, Handan Duman, Ezgi Topyildiz, Betul Ekici, Figen Gulen, and Esen Demir.
