General Surgery · Acibadem Atasehir Hospital, İstanbul Prof. Dr. Mert Erkan
✓ Medically verified profileProf. Dr. Mert Erkan
Prof. Dr. Mert Erkan is a general surgeon at Acibadem Atasehir Hospital in İstanbul, specializing in pancreas, liver and biliary tract diseases, including pancreatic cancer and iatrogenic biliary injuries, as well as digestive system surgery, robotic surgery and minimally invasive pancreatic surgery. He consults in Turkish and English and offers video consultation to international patients.
Accepting international patientsAbout Prof. Dr. Mert Erkan
Prof. Dr. Mert Erkan is a general surgeon at Acibadem Atasehir Hospital in İstanbul, where he works in the General Surgery unit. His subspecialties are the treatment of pancreas, liver and biliary tract diseases, digestive system diseases and surgery, and robotic surgery. He has more than 31 years in medicine and joined Acıbadem Healthcare Services in 2021.
Dr. Erkan graduated from İstanbul University İstanbul Faculty of Medicine in 1995 and completed his General Surgery specialization there in 2001, with a thesis on the retrospective evaluation of patients treated for iatrogenic biliary injury. From 2001 to 2003 he worked in the HPB Surgery Unit of the same faculty. Between 2003 and 2007 he was at Heidelberg University in General Surgery and at the European Pancreas Research Center, Heidelberg University, and in 2007 he received his PhD from Heidelberg University, awarded summa cum laude, with a thesis on the influence of the tumor-modulated microenvironment on pancreatic cancer behavior. From 2007 to 2014 he worked at Münih Teknik University, Klinikum rechts der Isar and the Pancreas Research Center, Münih Teknik University, where he completed advanced specialization in digestive system surgery in 2010 and became Associate Professor of General Surgery in 2011; his associate professorship was recognized by ÜAK equivalency in 2014. From 2014 to 2021 he was at Koç University Faculty of Medicine and its research laboratory, becoming Professor of General Surgery at Koç University in 2017, and he was affiliated with the Koç University Translational Medicine Research Center and the Koç University Health Sciences Institute from 2017 to 2021. He is a member of the International Hepato-Pancreato-Biliary Association (IHPBA), the European Pancreatic-Club/ EPC, the International Association of Pancreatology (IAP), European Digestive Surgery/ EDS and The European Consortium on Minimally Invasive Pancreatic Surgery, has served on committees of the Europan/African Hepato-Pancreato-Biliary Association, and was a board member of the Turkish Hepato-Pancreato-Biliary Surgery Association from 2015 to 2017. He has co-authored research publications on pancreatic cancer, including work on the tumor stroma and pancreatic stellate cells.
Clinical focus
Dr. Erkan’s clinical work centers on hepatopancreatobiliary surgery. He treats pancreatic diseases, including pancreatic cancer, as well as liver diseases and biliary tract diseases, and he also manages iatrogenic biliary injuries. His practice includes digestive system surgery more broadly.
Where clinically appropriate, he performs robotic surgery and minimally invasive pancreatic surgery. The suitability of any surgical approach is assessed individually, taking into account the patient’s diagnosis, imaging findings and overall condition.
How Dr. Erkan works with international patients
Dr. Erkan consults in Turkish and English, and interpreters can be arranged for other languages. The Acibadem international patient team coordinates the collection of prior reports and imaging, arranges appointments and organises the hospital visit. A first consultation typically covers the patient’s history and symptoms, a review of existing imaging and previous treatments, a clinical examination and a discussion of the available options. Video consultation is available for international patients who wish to discuss their case before traveling.
Meet Prof. Dr. Mert Erkan
Professor Mert Erkan Explains Colonic CancerWhat Dr. Erkan treats and performs
Each item opens the condition or treatment page with the care pathway for international patients.
Areas of practiceTreatment of pancreas, liver and biliary tract diseasesDigestive system diseases and surgeryRobotic surgery
Conditions treated
- Pancreatic diseases
- Pancreatic cancer
- Liver diseases
- Biliary tract diseases
- Iatrogenic biliary injuries
Procedures performed
- Hepatopancreatobiliary surgery
- Gallbladder surgery
- Robotic hernia surgery
- Robotic gallbladder surgery
- Gastric laparoscopic surgery
- Robotic thyroidectomy
- Robotic bariatric surgery
- Minimally invasive pancreatic surgery
Education, career and memberships
Education & training
Education
- 2017Professor of General Surgery, Koç University
- 2014ÜAK Associate Professorship Equivalency
- 2011Associate Professor of General Surgery, Münih Teknik University, Klinikum rechts der Isar
- 2010Advanced Specialization in Digestive System Surgery, Münih Teknik University, Klinikum rechts der Isar
- 2007PhD, Heidelberg University: Summa cum laude (En üst derecede onur). Tez: The influence of tumor modulated microenvironment on pancreatic cancer behavior.
- 2001İstanbul University İstanbul Faculty of Medicine General Surgery
- 2001General Surgery Specialist, İstanbul University, İstanbul Faculty of Medicine, Thesis: Retrospective evaluation of patients treated with a diagnosis of iatrogenic biliary injury
- 1995İstanbul University İstanbul Faculty of Medicine
Career
Professional Experience
- 2021Acıbadem Healthcare Services
- 2021Pancreatic Cancer Research Center, Acıbadem Mehmet Ali Aydınlar University İstanbul Türkiye
- 2017–2021Koç University Translational Medicine Research Center
- 2017–2021Koç University Health Sciences Institute
- 2014–2021Koç University Faculty of Medicine Research Laboratory
- 2014–2021Koç University Faculty of Medicine
- 2007–2014Pancreas Research Center, Münih Teknik University
- 2007–2014Münih Teknik University, Klinikum rechts der Isar
- 2003–2007Heidelberg University, General Surgery
- 2003–2007European Pancreas Research Center, Heidelberg University
- 2001–2003İstanbul University, İstanbul Faculty of Medicine, HPB Surgery Unit
- 1995–2001İstanbul University, İstanbul Faculty of Medicine
Memberships
Professional Memberships
- European Digestive Surgery/ EDS 2003-
- The European Consortium on Minimally Invasive Pancreatic Surgery
- İstanbul Medical Chamber 1995-2021
- Europan/African Hepato-Pancreato-Biliary Association Scientific and Research Committee Member: 2014 - Present / Program committee: 2015 - 2019 / Pancreatic terminology committee founding member 2021 -
- Bursa Medical Chamber 2021
- Deutsche Gesellschaft für Allgemein- und Viszeralchirurgie (DGAV) 2007 - 2014
- European Pancreatic-Club/ EPC 2003-
- Deutscher Pankreas-Club/ DPC 2003-
- Turkish Hepato-Pancreato-Biliary Surgery Association: 1998 Board Member: 2015-2017
- International Hepato-Pancreato-Biliary Association (IHPBA) 2001-
- International Association of Pancreatology (IAP) 2003-
Selected publications
Selected Publications
- Mutant KRAS-driven cancers depend on PTPN11/SHP2 phosphatase. Karpathaki, Marlena Kowalska, Ezgi Kaya-Aksoy, Liang Song, Eveline A Zeeuw van der Laan, María P López-Alberca, Marc Nazaré, Maximilian Reichert, Diet DA Ruess, GJ Heynen, KJ Ciecielski, J Ai, A Berninger, D Kabacaoglu, Kivanc Görgülü, Zahra Dantes, Sonja M Wörmann, Kalliope N Diakopoulos, Angeliki F
- Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma. Aayush Gupta, Irina Heid, Peter B Noël, Rickmer Braren, Mert Erkan,Nature medicine 2015 (280) PK Mazur, A Herner, SS Mello, M Wirth, S Hausmann, FJ Sánchez-Rivera, Shane M Lofgren, Timo Kuschma, Stephan A Hahn, Deepak Vangala, Marija Trajkovic-
- Intracellular autofluorescence: a biomarker for epithelial cancer stem cells. Manuel Hidalgo, Mert Erkan, …Nature methods 2014 (165) I Miranda-Lorenzo, J Dorado, E Lonardo, S Alcala, AG Serrano, Jenifer Clausell-Tormos, Michele Cioffi, Diego Megias, Sladjana Zagorac, Anamaria Balic,
- The role of stroma in pancreatic cancer: diagnostic and therapeutic implications. Nature reviews Gastroenterology & hepatology 2012 (476) M Erkan, S Hausmann, CW Michalski, AA Fingerle, M Dobritz, J Kleeff.
- StellaTUM: current consensus and discussion on pancreatic stellate cell research. Gut 2011 (365) M Erkan, G Adler, MV Apte, MG Bachem, M Buchholz, S Detlefsen, .
- Cancer-stellate cell interactions perpetuate the hypoxia-fibrosis cycle in pancreatic ductal adenocarcinoma Neoplasia 2009 (294) M Erkan, C Reiser-Erkan, CW Michalski, S Deucker, D Sauliunaite,
- Northern blot analysis for detection and quantification of RNA in pancreatic cancer cells and tissues Nature protocols 2009 (162) S Streit, CW Michalski, M Erkan, J Kleeff, H Friess.
- The activated stroma index is a novel and independent prognostic marker in pancreatic ductal adenocarcinoma. Clinical gastroenterology and hepatology 2008 (374) M Erkan, CW Michalski, S Rieder, C Reiser Erkan, I Abiatari, A Kolb
- Systematic review and meta-analysis of the role of defunctioning stoma in low rectal cancer surgery. Annals of surgery 2008 (592) N Hüser, CW Michalski, M Erkan, T Schuster, R Rosenberg, J Kleeff.
- Periostin creates a tumor-supportive microenvironment in the pancreas by sustaining fibrogenic stellate cell activity. Gastroenterology 2007 (330) M Erkan, J Kleeff, A Gorbachevski, C Reiser, T Mitkus, I Esposito, T Giese
- The neurotrophic factor artemin promotes pancreatic cancer invasion. Annals of surgery 2006 (159) GO Ceyhan, NA Giese, M Erkan, AG Kerscher, MN Wente, T Giese
- Loss of BNIP3 expression is a late event in pancreatic cancer contributing to chemoresistance and worsened prognosis. Oncogene 2005 (221) M Erkan, J Kleeff, I Esposito, T Giese, K Ketterer, MW Büchler, NA Giese, …


